Recombinant rabbit anti-MMAE (ADC Payload) monoclonal antibody, clone 8C4

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PRODUCT

  • SKU

    DMR1290-100ug

  • Size

    100 ug

  • Price

    $644

1
  • SKU

    DMR1290-500ug

  • Size

    500 ug

  • Price

    $1,934

1

This recombinant rabbit monoclonal antibody is part of a collection of rabbit mAbs against druggable targets developed by direct cloning from immunized rabbit B cells without hybridoma fusion. All antibodies have been fully sequenced and extensively validated by FACS and ELISA assays. Typically, multiple clones against each target are available for customer testing. The clones are available for licensing once the druggability of the antibodies has been validated by the customer, saving tremendous development time and effort. Antibody gene libraries from antigen-positive B cells are also available for further screening if the listed antibodies do not meet the customer's needs.

target ADC Payload MMAE
host species Rabbit
production host HEK293
clonality Monoclonal
clone number 8C4
iso type Rabbit IgG
formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 1 mg/ml, solubilize at RT for 30 min with occasional gentle mixing. It is recommended that 0.1% of HSA be added as a carrier protein for long term storage.
applications ELISA
dilution ELISA 1:5000-10000
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Elisa plates were pre-coated with IgG-MMAE (0.2ug/per well). Serial diluted anti-MMAE monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. Calculated from the data, EC50 for anti-MMAE monoclonal antibody binding with IgG-MMAE is 1.356ng/ml.


PRODUCT

  • SKU

    DMR1290-100ug

  • Size

    100 ug

  • Price

    $644

1
  • SKU

    DMR1290-500ug

  • Size

    500 ug

  • Price

    $1,934

1