Anti-human EGFR monoclonal antibody, Cetuximab biosimilar (Fab C225, IMC-225)

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PRODUCT

  • SKU

    DMS1063-100ug

  • Size

    100 ug

  • Price

    $350

1
This monoclonal antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
target EGFR
alias EGFR, ERBB, ERBB1, HER1, PIG61, mENA
gene id Uniprote ID: P00533
host species Chimeric
reactivity Human
iso type IgG1
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 minutes with occasional gentle tapping. It is recommended that 0.1% HSA be added as a carrier protein for long-term storage.
applications ELISA; Flow Cytometry
dilution ELISA 1:5000-10000
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.
note Other commonly used names in publications refering to this antibody: Fab C225, IMC-225

Images

ELISA plate coated with 2 ug/ml (100 ul/well) Human EGFR, His tagged protein binds to anti-EGFR neutralizing antibody in a linear range of 0.64-80 ng/ml.

EGFR protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis of anti-EGFR (Cetuximab) on Expi293 cells transfected with human EGFR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram)


PRODUCT

  • SKU

    DMS1063-100ug

  • Size

    100 ug

  • Price

    $350

1