Anti-human IL17RA monoclonal antibody, brodalumab biosimilar (AMG827, KHK4827)

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PRODUCT

  • SKU

    DMS1103-100ug

  • Size

    100 ug

  • Price

    $350

1
This monoclonal antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
target IL17RA
alias CD217, CDw217, IL-17RA, IL17R, CANDF5, hIL-17R
gene id Uniprote ID: Q96F46
host species Human
reactivity Human
iso type IgG2
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 minutes with occasional gentle tapping. It is recommended that 0.1% HSA be added as a carrier protein for long-term storage.
applications ELISA; Flow Cytometry
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.
note Other commonly used names in publications refering to this antibody: AMG827, KHK4827

Images

ELISA plate coated with 2 ug/ml (100 ul/well) Human IL17RA, His tagged protein binds to anti-IL17RA neutralizing antibody in a linear range of 3.2-80 ng/ml.

HEK293 cell line transfected with irrelevant protein (B) and human IL17RA (A) were surface stained with anti-IL17RA mAb 1 ug/ml (brodalumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.


PRODUCT

  • SKU

    DMS1103-100ug

  • Size

    100 ug

  • Price

    $350

1