Anti-human TNFRSF10B monoclonal antibody, tigatuzumab biosimilar (GEN-1029)

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PRODUCT

  • SKU

    DMS1167-100ug

  • Size

    100 ug

  • Price

    $350

1
This monoclonal antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
target TNFRSF10B
alias TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB
gene id Uniprote ID: O14763
host species Humanized
reactivity Human
iso type IgG1
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 minutes with occasional gentle tapping. It is recommended that 0.1% HSA be added as a carrier protein for long-term storage.
applications ELISA; Flow Cytometry
dilution ELISA 1:5000-10000
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.
note Other commonly used names in publications refering to this antibody: GEN-1029, HexaBody-DR5/DR5, Hx-DR5-01/05

Images

TNFRSF10B protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis of anti-TNFRSF10B (tigatuzumab) on Expi293 cells transfected with human TNFRSF10B (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram)

ELISA plate coated with 2 ug/ml (100 ul/well) Human TNFRSF10B, mFc tagged protein binds to anti-TNFRSF10B neutralizing antibody in a linear range of 3.2-80 ng/ml.


PRODUCT

  • SKU

    DMS1167-100ug

  • Size

    100 ug

  • Price

    $350

1