Anti-Human CD10, PE, Clone HI10a

Anti-Human CD10, PE, Clone HI10a

SKU Description Size Price Shipping  
JWF1003 Anti-Human CD10, PE, Clone HI10a  100T $200 Immediate Add To Shopping Cart
Datasheet
DescriptionThe HI10a monoclonal antibody reacts with neutral endopeptidase, a 100 kDa type II transmembrane glycoprotein, also known as common acute lymphoblastic leukemia antigen (CALLA). CD10 is expressed on B cell precursors, T cell precursors, and granulocytes. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides. This antibody is routinely tested by flow cytometric analysis to ensure the product quality.
Gene ID4311
Gene NameMME
AliasNot listed
Host SpeciesMouse
Reactivity SpeciesHuman
ClonalityMonoclonal
Clone Number HI10a
IsotypeIgG1, kappa
ConjugationPE
ConcentrationPre-tested ready-to-use solution
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography and conjugated with dye. The conjugated antibody was polished with chromatography and is free of unconjugated dye and unconjugated antibody.
ApplicationsFlow Cytometry
Suggested DilutionsSuggested amount of the reagent to be used: 10 µL antibody for a million cells or 100 µl human whole blood. Optimal dilutions must be determined by end users.
Storage ConditionsStore at 4°C and protect from light. DO NOT FREEZE. Stable for at least six months from date of shipment.
Shipping ConditionsAt Ambient Temperature
BackgroundThis gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
This product was manufactured by QuantoBio Inc.
Antibody Image
The Human peripheral blood granulocytes were stained with PE Mouse Anti-Human CD10 antibody (filled histogram) or the isotype control antibody (open histogram) at the same concentration.