Anti-Human CD62L, FITC, Clone DREG-56

Anti-Human CD62L, FITC, Clone DREG-56

SKU Description Size Price Shipping  
JWF1015 Anti-Human CD62L, FITC, Clone DREG-56  100T $160 Immediate Add To Shopping Cart
Datasheet
DescriptionThe DREG-56 monoclonal antibody reacts with human CD62L, a 76-95 kDa glycoprotein referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, and subsets of T, B, and NK cells. CD62L binds to a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCAM-1. These interactions mediate rolling of lymphocytes onto activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues. This antibody is routinely tested by flow cytometric analysis to ensure the product quality.
Gene ID6402
Gene NameSELL
AliasNot listed
Host SpeciesMouse
Reactivity SpeciesHuman
ClonalityMonoclonal
Clone Number DREG-56
IsotypeIgG1, kappa
ConjugationFITC
ConcentrationPre-tested ready-to-use solution
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography and conjugated with dye. The conjugated antibody was polished with chromatography and is free of unconjugated dye and unconjugated antibody.
ApplicationsFlow Cytometry
Suggested DilutionsSuggested amount of the reagent to be used: 10 µL antibody for a million cells or 100 µl human whole blood. Optimal dilutions must be determined by end users.
Storage ConditionsStore at 4°C and protect from light. DO NOT FREEZE. Stable for at least six months from date of shipment.
Shipping ConditionsAt Ambient Temperature
BackgroundThis gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
This product was manufactured by QuantoBio Inc.
Antibody Image
The Human whole blood cells were stained with FITC Mouse Anti-Human CD62L antibody (filled histogram) or the isotype control antibody (open histogram) at the same concentration.