Mouse anti-human CD89/FcaR/FCAR monoclonal antibody, clone MIP8a

Mouse anti-human CD89/FcaR/FCAR monoclonal antibody, clone MIP8a

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WZA1001 Mouse anti-human CD89/FcaR/FCAR monoclonal antibody, clone MIP8a 100 µg $298 2-7 days Add To Shopping Cart
Datasheet
DescriptionMouse anti-human CD89/FcaR/FCAR monoclonal antibody, clone MIP8a
Gene ID2204
Gene NameFCAR
AliasCD89
Host SpeciesMouse
Reactivity SpeciesHuman
ClonalityMonoclonal
Clone Number MIP8a
IsotypeIgG
ConjugationNone
Concentration1 mg/ml
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography with Protein A column.
ApplicationsWB, IP, ELISA
Suggested DilutionsFinal dilution for use is application-dependent and need to be determined by the end users. A final concentration of 1ug/ml is recommended as a starting point for most applications.
Storage ConditionsStore at 4°C. The antibody is stable for at least six months from date of shipment. For long-term storage, aliquote the antibody and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Shipping ConditionsAt ambient temperature, or with blue ice.
BackgroundThis gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Antibody Image
Neutrophil phagocytosis of IgA immune complexes in presence or absence (control) of MIP8a