Rat anti-mouse CTCF monoclonal antibody, Clone KT71

Rat anti-mouse CTCF monoclonal antibody, Clone KT71

SKU Description Size Price Shipping  
WZA1009 Rat anti-mouse CTCF monoclonal antibody, Clone KT71 100 µg $325 2-7 days Add To Shopping Cart
Datasheet
DescriptionRat anti-mouse CTCF monoclonal antibody, Clone KT71
Gene ID13018
Gene NameCTCF
Alias
Host SpeciesRat
Reactivity SpeciesMouse
ClonalityMonoclonal
Clone Number KT71
IsotypeIgG
ConjugationNone
Concentration1 mg/ml
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography with Protein A column.
ApplicationsWB, IP, ELISA
Suggested DilutionsFinal dilution for use is application-dependent and need to be determined by the end users. A final concentration of 1ug/ml is recommended as a starting point for most applications.
Storage ConditionsStore at 4°C. The antibody is stable for at least six months from date of shipment. For long-term storage, aliquote the antibody and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Shipping ConditionsAt ambient temperature, or with blue ice.
BackgroundThis gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Antibody Image