Mouse anti-human CFB/Complement factor B monoclonal antibody, Clone KT21

Mouse anti-human CFB/Complement factor B monoclonal antibody, Clone KT21

SKU Description Size Price Shipping  
WZA1028 Mouse anti-human CFB/Complement factor B monoclonal antibody, Clone KT21 100 µg $298 2-7 days Add To Shopping Cart
Datasheet
DescriptionMouse anti-human CFB/Complement factor B monoclonal antibody, Clone KT21
Gene ID629
Gene NameCFB
AliasBF; FB; BFD; GBG; CFAB; PBF2; AHUS4; FBI12; H2-Bf
Host SpeciesMouse
Reactivity SpeciesHuman
ClonalityMonoclonal
Clone Number KT21
IsotypeIgG
ConjugationNone
Concentration1 mg/ml
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography with Protein A column.
ApplicationsWB, IP, ELISA
Suggested DilutionsFinal dilution for use is application-dependent and need to be determined by the end users. A final concentration of 1ug/ml is recommended as a starting point for most applications.
Storage ConditionsStore at 4°C. The antibody is stable for at least six months from date of shipment. For long-term storage, aliquote the antibody and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Shipping ConditionsAt ambient temperature, or with blue ice.
BackgroundThis gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. 
Antibody Image
Sandwich ELISA usingKT21 coated plate and HRP conjugated KT24