Anti-mouse CD45R(B220),FITC, Clone Ra3.3A1/6.1

Anti-mouse CD45R(B220),FITC, Clone Ra3.3A1/6.1

SKU Description Size Price Shipping  
ZYF1073 Anti-mouse CD45R(B220),FITC, Clone Ra3.3A1/6.1 500 µg $233 Immediate Add To Shopping Cart
ZYF1074 Anti-mouse CD45R(B220),FITC, Clone Ra3.3A1/6.1 50 µg $38 Immediate Add To Shopping Cart
Datasheet
DescriptionAnti-mouse CD45R(B220) antibody, conjugated with FITC. This antibody has been extensively tested in flow cytometry.
Gene ID19264
Gene NamePTPRC
AliasNot listed
Host Species
Reactivity SpeciesMouse
ClonalityMonoclonal
Clone NumberRa3.3A1/6.1
IsotypeIgM,kappa
ConjugationFITC
Concentration0.5 mg/ml
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography and conjugated with dye. The conjugated antibody was polished with chromatography and is free of unconjugated dye and unconjugated antibody.
ApplicationsFlow Cytometry
Suggested DilutionsSuggested amount of the reagent to be used: <1 µg antibody for 106 cells in 100 µl staining buffer. Optimal dilutions must be determined by end users.
Storage ConditionsStore at 4°C and protect from light. DO NOT FREEZE. Stable for at least six months from date of shipment.
Shipping ConditionsAt Ambient Temperature
BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.  This antibody was manufactured by Sungene Biotech USA.
Antibody Image
C57BL/6 mouse splenocytes stained with FITC Anti-mouse CD45R/B220 (x-axis) and PE Anti-mouse CD3 (y-axis)