Anti-mouse TCR Vγ2, APC, Clone UC3-10A6

Anti-mouse TCR Vγ2, APC, Clone UC3-10A6

SKU Description Size Price Shipping  
ZYF1086 Anti-mouse TCR Vγ2, APC, Clone UC3-10A6 100 µg $198 Immediate Add To Shopping Cart
ZYF1087 Anti-mouse TCR Vγ2, APC, Clone UC3-10A6 25 µg $73 Immediate Add To Shopping Cart
Datasheet
DescriptionAnti-mouse TCR Vγ2 antibody, conjugated with APC. This antibody has been extensively tested in flow cytometry.
Gene ID110067
Gene NameTCRG
AliasNot listed
Host SpeciesArmenian hamster 
Reactivity SpeciesMouse
ClonalityMonoclonal
Clone NumberUC3-10A6
IsotypeIgG
ConjugationAPC
Concentration0.2 mg/ml
FormulationPBS pH 7.2, 0.09% NaN3,0.2% BSA
Purification MethodAntibody was purified by affinity chromatography and conjugated with dye. The conjugated antibody was polished with chromatography and is free of unconjugated dye and unconjugated antibody.
ApplicationsFlow Cytometry
Suggested DilutionsSuggested amount of the reagent to be used: <0.125 µg antibody for 106 cells in 100 µl staining buffer. Optimal dilutions must be determined by end users.
Storage ConditionsStore at 4°C and protect from light. DO NOT FREEZE. Stable for at least six months from date of shipment.
Shipping ConditionsAt Ambient Temperature
BackgroundT cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase.  This antibody was manufactured by Sungene Biotech USA.
Antibody Image
C57BL/6 mouse splenocytes CD3+ stained with FITC Anti-mouse gdTCR (x-axis) and APC Anti-mouse TCR V?2 (y-axis)