Human FGF2 Protein (basic fibroblast growth factor), Made in Sf21 Insect Cell, with His Tag

Human FGF2 Protein (basic fibroblast growth factor), Made in Sf21 Insect Cell, with His Tag

SKU Description Size Price Shipping  
OP20181 Human FGF2 Protein (basic fibroblast growth factor), Made in Sf21 Insect Cell, with His Tag 5µg $313 Immediate Add To Shopping Cart
OP20182 Human FGF2 Protein (basic fibroblast growth factor), Made in Sf21 Insect Cell, with His Tag 12.5µg $624 Immediate Add To Shopping Cart
Other VersionsHuman thermostable FGF2 made from stable HEK293 cells, suitable for stem cell culture.
Human FGF2 made from E.Coli with No tag.
Human FGF2 made from Sf21 cells with His tag.
Mouse FGF2 made from E. Coli with No tag.
Datasheet
DescriptionAcidic fibroblast growth factor (FGF-1) and basic fibroblast growth factor (FGF-2) are ubiquitous cytokines found in many tissues. They have effects on multiple cell types derived from mesoderm and neuroectoderm, including endothelial cells . FGF proteins are small peptides of 155 to 268 amino acid residues . The degree of sequence identity between different family members is 30-60% in a "central domain" of ~120 amino acids. This domain confers to FGFs a common tertiary structure and the ability to bind to heparin . Secreted FGFs signal to target cells by binding and activating cell-surface tyrosine kinase FGF receptors (FGFRs). The function of FGFs and FGFRs during embryonic development and adult physiology has been addressed by gain- and loss-of-function experiments in several animal model organisms. These studies have shown that FGFs act as key regulators of developmental events .
Gene ID2247
Gene NameFGF2
AliasBFGF, FGFB
Host SpeciesHuman
Production HostSf21 Insect Cell
TagsHis Tag
Purity> 95% as determined by SDS-PAGE
Bio Activity1 unit equals 1 nanogram of purified protein; 20 units are sufficient in cell culture experiments.
EndotoxinNot Tested
Formulation20 mM Tris-Cl (pH 7.9) 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA
Concentration350 µg/ml
ReconsitutionAlready in liquid form.
Storage-80 °C
ShippingDry Ice
Background
GenBank Accession #: NM_002006
Amino Acid Sequence:
MVGVGGGDVE DVTPRPGGCQ ISGRGARGCN GIPGAAAWEA ALPRRRPRRH PSVNPRSRAA GSPRTRGRRT EERPSGSRLG DRGRGRALPG GRLGGRGRGR APERVGGRGR GRGTAAPRAA PAARGSRPGP AGTMAAGSIT TLPALPEDGG SGAFPPGHFK DPKRLYCKNG GFFLRIHPDG RVDGVREKSD PHIKLQLQAE ERGVVSIKGV CANRYLAMKE DGRLLASKCV TDECFFFERL ESNNYNTYRS RKYTSWYVAL KRTGQYKLGS KTGPGQKAIL FLPMSAKS
Protein Image