Human SRSF2/SC35/SFRS2 Protein, Made in Sf21 Insect Cell, with His Tag

Human SRSF2/SC35/SFRS2 Protein, Made in Sf21 Insect Cell, with His Tag

SKU Description Size Price Shipping  
OP30031 Human SRSF2/SC35/SFRS2 Protein, Made in Sf21 Insect Cell, with His Tag 5µg $341 Immediate Add To Shopping Cart
OP30032 Human SRSF2/SC35/SFRS2 Protein, Made in Sf21 Insect Cell, with His Tag 12.5µg $680 Immediate Add To Shopping Cart
Other VersionsBiotin-labeled and heavy-labeled (C13 and N15) versions of this protein are also available. Please contact us for more information.
Datasheet
DescriptionSC35, a member of the SR protein family, is an essential pre-mRNA splicing factor and can function as an essential splicing factor as well as an alternative splicing factor . Phosphorylation of serine residues located within the SR domain directly regulates SC35 activity and compartmentalization of other SR splicing factors . In addition to interacting with RNA and other splicing factors, SC35 has been shown to interact either directly or indirectly with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II, thereby suggesting a potential role of SC35 in coordinating transcription and pre-mRNA splicing .
Gene ID6427
Gene NameSRSF2
AliasPR264, SC-35
Host SpeciesHuman
Production HostSf21 Insect Cell
TagsHis Tag
Purity> 95% as determined by SDS-PAGE
Bio Activity1 unit equals 1 nanogram of purified protein. 1-5 units are the amount sufficient for a gel mobility shift assay in a 20 µl reaction, 100 units are sufficient for a protein-protein interaction assay and 100-500 units are required for a splicing assay in a 20 µl reaction.
EndotoxinNot Tested
Formulation20 mM Tris-Cl (pH 7.9) 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA
Concentration650 µg/ml
ReconsitutionAlready in liquid form.
Storage-80 °C
ShippingDry Ice
Background
GenBank Accession #: NM_003016
Amino Acid Sequence:
GRPPPDVEGM TSLKVDNLTY RTSPDTLRRV FEKYGRVGDV YIPRDRYTKE SRGFAFVRFH DKRDAEDAMD AMDGAVLDGR ELRVQMARYG RPPDSHHSRR GPPPRRYGGG GYGRRSRSPR RRRRSRSRSR SRSRSRSRSR YSRSKSRSRT RSRSRSTSKS RSARRSKSKS SSVSRSRSRS RSRSRSRSPP PVSKRESKSR SRSKSPPKSP EEEGAVSS
Protein Image
SDS-PAGE alysis of recombint SRSF2