Recombinant IL22 Proteins - SPEED BioSystems

Recombinant IL-22 Proteins

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Cytokines

Interleukin-22 (IL22) is a cytokine belonging to the IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22’s biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. SPEED Biosystems provides the following IL22 recombinant proteins.


SKU Protein Name Species Amino Acid Sequence Production Host Tags
YSP7569 IL22 Human Ala34-Ile179 of Uniprot Q9GZX6 E.coli None
YSP7571 IL22 Human Ala34-Ile179 of Uniprot Q9GZX6 HEK293 hIgG2 Fc
YSP7573 IL22 Human Ala34-Ile179 of Uniprot Q9GZX6 HEK293 hIgG4 Fc
YCP5526 IL22 Human Ala34-Ile179 of Uniprot Q9GZX6 HEK293 His
YSP7645 IL22 Mouse Leu34-Val179 of Uniprot Q9JJY9 HEK293 mFc
YSP7647 IL22 Mouse Leu34-Val179 of Uniprot Q9JJY9 HEK293 None
YSP1515 IL22 Mouse Leu34-Val179 of Uniprot Q9JJY9 E.coli None