Anti-human ALCAM / CD166 monoclonal antibody, praluzatamab biosimilar

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PRODUCT

  • SKU

    DMS1002-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: CX-191
target ALCAM / CD166
alias ALCAM, MEMD
gene id Uniprot ID: Q13740
host species Humanized
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications Flow Cyt
dilution Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

CD166 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with 15ug/mL Anti-CD166 (praluzatamab biosimilar) mAb on Expi293 cells transfected with Human CD166 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram),and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

Flow cytometry analysis of antigen binding of anti-human CD166 mAb. (A) The antibody does not bind to K562 cells that do not express CD166. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CD166-expressing Hela cells, indicating strong binding of The antibody to CD166. Antibodies were incubated at 5 ug/mL.

Flow cytometry analysis of antigen binding of anti-human CD166 mAb. (A) The antibody does not bind to K562 cells that do not express CD166. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CD166-expressing Huh7 cells, indicating strong binding of The antibody to CD166. Antibodies were incubated at 5 ug/mL.


PRODUCT

  • SKU

    DMS1002-100ug

  • Size

    100ug

  • Price

    $350

1