Anti-human CEACAM6 monoclonal antibody, tinurilimab biosimilar

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PRODUCT

  • SKU

    DMS1050-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: BAY-1834942
target CEACAM6
alias CD66c, CEAL, NCA
gene id Uniprot ID: P40199
host species Humanized
reactivity Human
iso type Human IgG2 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human CEACAM6 Protein, His Tag binds to Anti-CEACAM6 Neutralizing antibody in a linear range of 0.61?156.25 ng/mL.

Flow cytometry analysis with 1 ug/mL Anti-CEACAM6 (tinurilimab biosimilar) mAb on Expi293 cells transfected with Human CEACAM6 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis of antigen binding of anti-human CEACAM6 mAb. (A) The antibody does not bind to Jurkat cells that do not express CEACAM6. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CEACAM6-expressing TT cells, indicating strong binding of The antibody to CEACAM6. Antibodies were incubated at 5 ug/mL.


PRODUCT

  • SKU

    DMS1050-100ug

  • Size

    100ug

  • Price

    $350

1