Anti-human CSF1R monoclonal antibody, cabiralizumab biosimilar

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PRODUCT

  • SKU

    DMS1055-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: FPA-008, FPA008
target CSF1R
alias CSF1R, C-FMS, CD115, CSFR, FIM2, FMS, M-CSFR
gene id Uniprot ID: P07333
host species Humanized
reactivity Human
iso type Human IgG4 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Flow cytometry analysis with Anti-CSF1R mAb 1 ug/ml (cabiralizumab) on Expi293 cells transfected with human CSF1R (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram) .

ELISA plate pre-coated by 1 ug/ml (100 ul/well) Human CSF1R , His tagged protein binds to Anti-CSF1R Neutralizing antibody in a linear range of 0.2-16 ng/ml.

Flow cytometry analysis of antigen binding of anti-human CSF1R mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with CSF1R-expressing THP-1 cells, indicating strong binding of The antibody to CSF1R. Antibodies were incubated at 2 ug/mL.


PRODUCT

  • SKU

    DMS1055-100ug

  • Size

    100ug

  • Price

    $350

1