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DMS1101-100ug
100ug
$350
| note | Other commonly used names in publications refering to this antibody: RO4858696-000, teprotumumab-trbw |
| target | IGF-1R |
| alias | CD221, IGFIR, IGFR, JTK13 |
| gene id | Uniprot ID: P08069 |
| host species | Human |
| reactivity | Human |
| iso type | Human IgG1 (E356D,M358L) kappa |
| formulation | Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization. |
| reconstitution | Reconstitute lyophilized powder with water to a concentration of 100 ug/ml |
| applications | Flow Cyt |
| dilution | Flow Cyt 1:100 |
| shipping | Shipped at ambient conditions. |
| storage | Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months. |
IGF-1R protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with 1ug/mL Anti-IGF-1R (teprotumumab biosimilar) mAb on Expi293 cells transfected with human IGF-1R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram),and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
Flow cytometry analysis of antigen binding of anti-human IGF-1R mAb. (A) The antibody does not bind to Jurkat cells that do not express IGF-1R. (B) A clear peak shift of The antibody was seen compared to the control when incubated with IGF-1R-expressing Hela cells, indicating strong binding of The antibody to IGF-1R. Antibodies were incubated at 5 ug/mL.
Flow cytometry analysis of antigen binding of anti-human IGF-1R mAb. (A) The antibody does not bind to Jurkat cells that do not express IGF-1R. (B) A clear peak shift of The antibody was seen compared to the control when incubated with IGF-1R-expressing MCF-7 cells, indicating strong binding of The antibody to IGF-1R. Antibodies were incubated at 5 ug/mL.
DMS1101-100ug
100ug
$350