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DMS1111-100ug
100ug
$350
| note | Other commonly used names in publications refering to this antibody: CSL-362-AML, CSL362, JNJ-56022473 |
| target | IL3RA / CD123 |
| alias | CD123, IL3R, IL3RA |
| gene id | Uniprot ID: P26951 |
| host species | Humanized |
| reactivity | Human |
| iso type | Human IgG1 kappa |
| formulation | Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization. |
| reconstitution | Reconstitute lyophilized powder with water to a concentration of 100 ug/ml |
| applications | ELISA, Flow Cyt |
| dilution | ELISA 1:5000-10000; Flow Cyt 1:100 |
| shipping | Shipped at ambient conditions. |
| storage | Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months. |
ELISA plate pre-coated by 2 ug/ml (100 uL/well) Human CD123, hFc-His tagged protein binds to Anti-CD123 Neutralizing antibody in a linear range of 0.98-26.70 ng/ml.
HEK293 cell line transfected with irrelevant protein (B) and human CD123 (A) were surface stained with anti-CD123 neutralizing antibody 1ug/ml (talacotuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
Flow cytometry analysis of antigen binding of anti-human CD123 mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with CD123-expressing 8226 cells, indicating strong binding of The antibody to CD123. Antibodies were incubated at 2 ug/mL.
Flow cytometry analysis of antigen binding of anti-human CD123 mAb. (A) The antibody does not bind to CHO-S cells that do not express CD123. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CD123-expressing THP-1 cells, indicating strong binding of The antibody to CD123. Antibodies were incubated at 5 ug/mL.
DMS1111-100ug
100ug
$350