Anti-human NECTIN4 monoclonal antibody, enfortumab biosimilar

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PRODUCT

  • SKU

    DMS1136-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: enfortumab
target NECTIN4
alias EDSS1, LNIR, nectin-4, PRR4, PVRL4
gene id Uniprot ID: Q96NY8
host species Human
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Flow cytometry analysis with 1 ug/mL Anti-Nectin-4 (enfortumab biosimilar) mAb on Expi293 cells transfected with Human Nectin-4 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human NECTIN-4 Protein, His Tag binds to Anti-Nectin-4 Neutralizing antibody in a linear range of 0.61?39.06 ng/mL.

Flow cytometry analysis of antigen binding of anti-human Nectin-4 mAb. (A) The antibody does not bind to 293T cells that do not express Nectin-4. (B) A clear peak shift of The antibody was seen compared to the control when incubated with Nectin-4-expressing A431 cells, indicating strong binding of The antibody to Nectin-4. Antibodies were incubated at 2 ug/mL.


PRODUCT

  • SKU

    DMS1136-100ug

  • Size

    100ug

  • Price

    $350

1