Anti-human ROR1 monoclonal antibody, zilovertamab biosimilar

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PRODUCT

  • SKU

    DMS1145-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: UC-961, cirmtuzumab
target ROR1
alias ROR1, NTRKR1
gene id Uniprot ID: Q01973
host species Humanized
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human ROR1, His tagged protein binds to Anti-ROR1 Neutralizing antibody in a linear range of 0.64-16 ug/ml.

Flow cytometry analysis with Anti-ROR1 (zilovertamab biosimilar) mAb 15 ug/mL on Expi293 cells transfected with Human ROR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human ROR1 (30-164) Protein with hFc Tag can bind to Anti-ROR1 (zilovertamab biosimilar) mAb in a linear range of 40-200 ng/mL. In order to specifically detect The antibody, mouse anti-human Fab-specific antibody was used as detection antibody.

Flow cytometry analysis of antigen binding of anti-human ROR1 mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with ROR1-expressing 8226 cells, indicating strong binding of The antibody to ROR1. Antibodies were incubated at 2 ug/mL.


PRODUCT

  • SKU

    DMS1145-100ug

  • Size

    100ug

  • Price

    $350

1