Anti-human TM4SF1 monoclonal antibody, AGX101 biosimilar

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PRODUCT

  • SKU

    DMS1163-100ug

  • Size

    100ug

  • Price

    $350

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This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: AGX101
target TM4SF1
alias M3S1, TAAL6
gene id Uniprot ID: P30408
host species Humanized
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications Flow Cyt
dilution Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Flow cytometry analysis with 1 ug/mL Anti-TM4SF1 (AGX101 biosimilar) mAb on Expi293 cells transfected with Human TM4SF1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plates were pre-coated with 0.5ug/per well purified human TM4SF1 full length membrane nanoparticles . Serial diluted Anti-TM4SF1 (AGX101 biosimilar) mAb solutions were added, washed, and incubated with secondary antibody before ELISA reading. From above data, the EC50 for Anti-TM4SF1 (AGX101 biosimilar) mAb binding with TM4SF1 MNPs is 4.174ng/ml.

ELISA plates were pre-coated with Flag Tag TM4SF1-Nanodisc . Serial diluted Anti-TM4SF1 (AGX101 biosimilar) mAb were added, washed, and incubated with secondary antibody before ELISA reading. From above data, the EC50 for Anti-TM4SF1 (AGX101 biosimilar) mAb binding with TM4SF1-Nanodisc is 15.97ng/ml.

FACS analysis of TM4SF1 MNPs. A. TM4SF1 MNP were stained only with Goat anti-human 2nd antibody. B. Negative control MNP samples were stained with Anti-TM4SF1 (AGX101 biosimilar) mAb at 2ug/mL, followed by Goat anti-human IgG 488 secondary antibody. C. TM4SF1 MNP samples were stained with anti-CCR8 antibody (an irrelevant antibody) at 2ug/mL, followed by Goat anti-human 2nd antibody. D. TM4SF1 MNP samples were stained with Anti-TM4SF1 (AGX101 biosimilar) mAb at 2ug/mL, followed by Goat anti-human 2nd antibody.


PRODUCT

  • SKU

    DMS1163-100ug

  • Size

    100ug

  • Price

    $350

1