Anti-human ERBB3 / HER3 monoclonal antibody, seribantumab biosimilar

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PRODUCT

  • SKU

    DMS1644-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: MM-121, MM121, SAR256212
target ERBB3 / HER3
alias HER3, ERBB3
gene id Uniprot ID: P21860
host species Human
reactivity Human
iso type Human IgG2 (S378A) kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000, Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human Her3 Protein with His Tag can bind to Anti-Her3 (seribantumab biosimilar) mAb in a linear range of 0.13-16 ng/mL.

Flow cytometry analysis of antigen binding of anti-human Her3 mAb. (A) The antibody does not bind to 293T cells that do not express Her3. (B) A clear peak shift of The antibody was seen compared to the control when incubated with Her3-expressing HT55 cells, indicating strong binding of The antibody to Her3. Antibodies were incubated at 5 ug/mL.

Flow cytometry analysis with 1ug/mL Anti-Her3 (seribantumab biosimilar) mAb on HEK293 cells transfected with Human Her3 protein (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).


PRODUCT

  • SKU

    DMS1644-100ug

  • Size

    100ug

  • Price

    $350

1