Recombinant rabbit anti-human SLAMF7 / CS1 monoclonal antibody, clone DM9

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PRODUCT

  • SKU

    DMR1355-100ug

  • Size

    100ug

  • Price

    $669

1
  • SKU

    DMR1355-500ug

  • Size

    500ug

  • Price

    $2,010

1
This recombinant rabbit monoclonal antibody is part of a collection of rabbit mAbs against druggable targets developed by direct cloning from immunized rabbit B cells without hybridoma fusion. All antibodies have been fully sequenced and extensively validated by FACS and ELISA assays. Typically, multiple clones against each target are available for customer testing. The clones are available for licensing once the druggability of the antibodies has been validated by the customer, saving tremendous development time and effort. Antibody gene libraries from antigen-positive B cells are also available for further screening if the listed antibodies do not meet the customer's needs.
target SLAMF7 / CS1
alias SLAM7 (19A, CD319, CRACC, CS1)
gene id Uniprot ID: Q9NQ25
host species Rabbit
production host HEK293
reactivity Human
clonality Monoclonal
clone number DM9
iso type Rabbit IgG
conjugate Unconjugated
formulation Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 min with occasional gentle mixing. It is recommended that 0.1% of HSA be added as a carrier protein for long term storage.
applications ELISA, Flow Cytometry
dilution Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Expi 293 cell line transfected with irrelevant protein (left) and human CS1 (right) were surface stained with Rabbit anti-CS1monoclonal antibody 1ug/ml (clone: DM9) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Affinity ranking of different Rabbit anti-CS1 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Phylogenetic analysis of amino acid sequence of different Rabbit Anti-CS1 mAb clones. A) Heavy chain and B) Light chain.

Flow cytometry data of serially titrated Rabbit anti-CS1 monoclonal antibody (clone: DM9) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Flow cytometry analysis of antigen binding of rabbit anti-human CS1 mAb. (A) The antibody does not bind to 293T cells that do not express CS1. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CS1-expressing MM.1S cells, indicating strong binding of The antibody to CS1. Antibodies were incubated at 2 ug/mL.

Related Products

PRODUCT

  • SKU

    DMR1355-100ug

  • Size

    100ug

  • Price

    $669

1
  • SKU

    DMR1355-500ug

  • Size

    500ug

  • Price

    $2,010

1

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