Anti-human CD276 / B7-H3 monoclonal antibody, enoblituzumab biosimilar

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PRODUCT

  • SKU

    DMS1029-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: MG-A271, MGA271
target CD276 / B7-H3
alias B7-H3, CD276, B7 homolog 3
gene id Uniprot ID: Q5ZPR3
host species Humanized
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human B7-H3, mFc-His tagged protein binds to Anti-B7-H3 Neutralizing antibody in a linear range of 0.24-31.25 ng/ml.

Flow cytometry analysis with 1ug/mL Anti-B7-H3 (enoblituzumab biosimilar) mAb on Hela cells (Blue histogram) or isotype control mAb on Hela cells (Red histogram).

Flow cytometry analysis of antigen binding of anti-human B7-H3 mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with B7-H3-expressing Hela cells, indicating strong binding of The antibody to B7-H3. Antibodies were incubated at 2 ug/mL.


PRODUCT

  • SKU

    DMS1029-100ug

  • Size

    100ug

  • Price

    $350

1