Anti-human CD70 monoclonal antibody, vorsetuzumab biosimilar

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PRODUCT

  • SKU

    DMS1041-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: SGN-70, h1F6
target CD70
alias CD70, CD27L, CD27LG, TNFSF7
gene id Uniprot ID: P32970
host species Human
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human CD70, mFc-His tagged protein binds to Anti-CD70 Neutralizing antibody in a linear range of 3.91-139.9 ng/ml.

HEK293 cell line transfected with irrelevant protein (B) and human CD70 (A) were surface stained with anti-CD70 neutralizing antibody 1ug/ml (vorsetuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Flow cytometry analysis of antigen binding of anti-human CD70 mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with CD70-expressing THP1 cells, indicating strong binding of The antibody to CD70. Antibodies were incubated at 2 ug/mL.


PRODUCT

  • SKU

    DMS1041-100ug

  • Size

    100ug

  • Price

    $350

1