Anti-human CD74 monoclonal antibody, milatuzumab biosimilar

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PRODUCT

  • SKU

    DMS1043-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: CD74-DOX (ADC), hLL1, hLL1-DOX (ADC), MEDI-115
target CD74
alias DHLAG
gene id Uniprot ID: P04233
host species Humanized
reactivity Human
iso type Human IgG1 (K214R) kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000, Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

Flow cytometry analysis with 15ug/mL Anti-CD74 (milatuzumab biosimilar) mAb on Expi293 cells transfected with Human CD74 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human CD74 (73-296) Protein, hFc Tag binds to Anti-CD74 (milatuzumab biosimilar) mAb in a linear range of 0.64?16 ng/mL.

Flow cytometry analysis of antigen binding of anti-human CD74 mAb. (A) The antibody does not bind to 293T cells that do not express CD74. (B) A clear peak shift of The antibody was seen compared to the control when incubated with CD74-expressing Raji cells, indicating strong binding of The antibody to CD74. Antibodies were incubated at 5 ug/mL.


PRODUCT

  • SKU

    DMS1043-100ug

  • Size

    100ug

  • Price

    $350

1