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DMS1157-100ug
100ug
$350
| note | Other commonly used names in publications refering to this antibody: IMMU-132, hRS7-SN-38, hRS7-SN-38-ADC, hRS7-[CL-SN-38], hrS7-SN-38 |
| target | TACSTD2 / Trop2 |
| alias | TACSTD2, GA733-1, M1S1, TROP2 |
| gene id | Uniprot ID: P09758 |
| host species | Humanized |
| reactivity | Human |
| iso type | Human IgG1 kappa |
| formulation | Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization. |
| reconstitution | Reconstitute lyophilized powder with water to a concentration of 100 ug/ml |
| applications | ELISA, Flow Cyt |
| dilution | ELISA 1:5000-10000; Flow Cyt 1:100 |
| shipping | Shipped at ambient conditions. |
| storage | Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months. |
ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human Trop2, mFc-His tagged protein binds to Anti-Trop2 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.
HEK293 cell line transfected with irrelevant protein (B) and human Trop2 protein (A) were surface stained with anti-Trop2 neutralizing antibody 1ug/ml (sacituzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
Flow cytometry analysis of antigen binding of anti-human Trop2 mAb. (A) The antibody does not bind to 293T cells that do not express Trop2. (B) A clear peak shift of The antibody was seen compared to the control when incubated with Trop2-expressing A431 cells, indicating strong binding of The antibody to Trop2. Antibodies were incubated at 2 ug/mL.
DMS1157-100ug
100ug
$350