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DMS1167-100ug
100ug
$350
| note | Other commonly used names in publications refering to this antibody: GEN-1029, HexaBody-DR5/DR5, Hx-DR5-01/05 |
| target | TNFRSF10B |
| alias | TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB |
| gene id | Uniprot ID: O14763 |
| host species | Humanized |
| reactivity | Human |
| iso type | Human IgG1 kappa |
| formulation | Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization. |
| reconstitution | Reconstitute lyophilized powder with water to a concentration of 100 ug/ml |
| applications | ELISA, Flow Cyt |
| dilution | ELISA 1:5000-10000 |
| shipping | Shipped at ambient conditions. |
| storage | Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months. |
TNFRSF10B protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-TNFRSF10B (tigatuzumab) on Expi293 cells transfected with human TNFRSF10B (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram)
ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human TNFRSF10B, mFc tagged protein binds to Anti-TNFRSF10B Neutralizing antibody in a linear range of 3.2-80 ng/ml.
Flow cytometry analysis of antigen binding of anti-human TNFRSF10B mAb. (A) The antibody does not bind to TT cells that do not express TNFRSF10B. (B) A clear peak shift of The antibody was seen compared to the control when incubated with TNFRSF10B-expressing SNU-5 cells, indicating strong binding of The antibody to TNFRSF10B. Antibodies were incubated at 5 ug/mL.
DMS1167-100ug
100ug
$350