Anti-human TNFRSF8 / CD30 monoclonal antibody, brentuximab biosimilar

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PRODUCT

  • SKU

    DMS1174-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: SGN-35, cAC10-Val-Cit-MMAE
target TNFRSF8 / CD30
alias TNFRSF8, CD30, D1S166E, Ki-1
gene id Uniprot ID: P28908
host species Chimeric
reactivity Human
iso type Human IgG1 kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000; Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated by 2 ug/ml (100 uL/well) Human CD30, His tagged protein binds to Anti-CD30 Neutralizing antibody in a linear range of 0.13-80.0 ng/ml.

Flow cytometry analysis of antigen binding of anti-human CD30 mAb. (A) A clear peak shift of The antibody was seen compared to the control when incubated with CD30-expressing 8226 cells, indicating strong binding of The antibody to CD30. Antibodies were incubated at 2 ug/mL.

Flow cytometry analysis with Anti-CD30 (brentuximab) on HEK293 cells transfected with human CD30 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).


PRODUCT

  • SKU

    DMS1174-100ug

  • Size

    100ug

  • Price

    $350

1