Anti-human ACVR2B monoclonal antibody, bimagrumab biosimilar

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PRODUCT

  • SKU

    DMS1611-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: BYM338
target ACVR2B
alias AVR2B, ACTR-IIB
gene id Uniprot ID: Q13705
host species Human
reactivity Human
iso type Human IgG1 (K214R,L234A,L235A) kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000, Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human ACVR2A (20-135) Protein with His Tag can bind to Anti-ACVR2B (bimagrumab biosimilar) mAb in a linear range of 0.13-16 ng/mL.

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human ACVR2B (19-137) Protein with His Tag can bind to Anti-ACVR2B (bimagrumab biosimilar) mAb in a linear range of 0.64-80 ng/mL.

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human ACVR2B Protein with hFc Tag can bind to Anti-ACVR2B (bimagrumab biosimilar) mAb in a linear range of 0.64-80 ng/mL.In order to specifically detect The antibody, mouse anti-human Fab-specific antibody was used as detection antibody.

Flow cytometry analysis with 15ug/mL Anti-ACVR2B (bimagrumab biosimilar) mAb on HEK293 cells transfected with Human ACVR2B protein (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis with 1ug/mL Anti-ACVR2B (bimagrumab biosimilar) mAb on HEK293 cells transfected with Human ACVR2A protein (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).


PRODUCT

  • SKU

    DMS1611-100ug

  • Size

    100ug

  • Price

    $350

1