Anti-human IL31RA monoclonal antibody, nemolizumab biosimilar

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PRODUCT

  • SKU

    DMS1620-100ug

  • Size

    100ug

  • Price

    $350

1
This antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
note Other commonly used names in publications refering to this antibody: CIM 331, CIM331
target IL31RA
alias CRL, GPL, CRL3, GLMR, GLM-R, PLCA2, hGLM-R, IL-31RA, PRO21384, zcytoR17
gene id Uniprot ID: Q8NI17
host species Humanized
reactivity Human
iso type Human IgG2 (C135S,R137K,E141G,S142G,C223S,H268Q,R355Q,S378A,Q419E) kappa
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml
applications ELISA, Flow Cyt
dilution ELISA 1:5000-10000, Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.

Images

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human IL31RA (20-225) Protein with hFc Tag can bind to Anti-IL31RA (nemolizumab biosimilar) mAb in a linear range of 16-400 ng/mL. In order to specifically detect The antibody, mouse human Fab-specific antibody was used as detection antibody.

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human IL31RA (20-225) Protein with mFc Tag can bind to Anti-IL31RA (nemolizumab biosimilar) mAb in a linear range of 0.13-16 ng/mL.

ELISA plate pre-coated with2 ug/mL (100 uL/well) Human IL31RA Protein with His Tag can bind to Anti-IL31RA (nemolizumab biosimilar) mAb in a linear range of 0.13-16 ng/mL.

Flow cytometry analysis with 1ug/mL Anti-IL31RA (nemolizumab biosimilar) mAb on HEK293 cells transfected with Human IL31RA and OSMR protein (Blue histogram) or HEK293 transfected with Human OSMR protein (Red histogram).


PRODUCT

  • SKU

    DMS1620-100ug

  • Size

    100ug

  • Price

    $350

1