Cynomolgus Integrin alpha 4 beta 7 (ITGA4 and ITGB7) heterodimer protein, produced in HEK293

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PRODUCT

  • SKU

    YCD3217-100ug

  • Size

    100ug

  • Price

    $647

1
  • SKU

    YCD3217-1mg

  • Size

    1mg

  • Price

    $4,536

1
Cynomolgus ITGA4&ITGB7 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 111.6 kDa (ITGA4) & 81.6 kDa (ITGB7). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a His tag and subunit ITGB7 contains no tag but a basic tail at the C-terminus. The protein migrates at 60-70 kDa, 95-120 kDa (ITGB7) and 130-150 kDa (ITGA4) in SDS-PAGE due to glycosylation.
gene name ITGA4&ITGB7
gene id NCBI# XP_005573683.2 (ITGA4) & XP_005571028.2 (ITGB7)
host species Cynomolgus
production host HEK293
tags C-10xHis, Tag-free
purity >90% as determined by SDS-PAGE.
endotoxin No endotoxin was detected in final prodcut using LAL method to the method's sensitivity level (< 1.0 EU/ug).
formulation 50 mM Tris, 150 mM NaCl, pH7.5
reconstitution Reconstitute lyophilized powder with water to a concentration of no less than 100 ug/ml. It is recommended that 0.1% of HSA be added as a carrier protein for long term storage.
shipping Shipped at ambient conditions
storage Lyophilized form is stable for 2 weeks at room temperature or for 12 months at 4-8°C. Keep at -20°C or lower for long term storage. After reconstitution, store at 4°C for 2-7 days or at below -20°C for up to 3 months.

Images

ELISA: Immobilized Cynomolgus ITGA4&ITGB7 Heterodimer Protein at 1 ug/mL (100 uL/well) binds to Anti-Human Integrin alpha 4 beta 7 MAb, Human IgG1(ADCC Disable) with a linear range of 0.0005-0.125 ug/mL .

ELISA: Immobilized Cynomolgus ITGA4&ITGB7 Heterodimer Protein at 5 ug/mL (100 uL/well) binds to Vedolizumab with a linear range of 0.06-1 ng/mL .

SDS-PAGE analysis of ITGA4&ITGB7 protein


PRODUCT

  • SKU

    YCD3217-100ug

  • Size

    100ug

  • Price

    $647

1
  • SKU

    YCD3217-1mg

  • Size

    1mg

  • Price

    $4,536

1