Home/ Products / Recombinant Rabbit McAbs
DMR1384-100ug
100ug
$657
DMR1384-500ug
500ug
$1,971
| target | TNFRSF17 / BCMA |
| alias | TNFRSF17 |
| gene id | Uniprot ID: Q02223 |
| host species | Rabbit |
| production host | HEK293 |
| reactivity | Human |
| clonality | Monoclonal |
| clone number | DM4 |
| iso type | Rabbit scfv |
| conjugate | Unconjugated |
| formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization. |
| reconstitution | Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 min with occasional gentle mixing. It is recommended that 0.1% of HSA be added as a carrier protein for long term storage. |
| applications | Flow Cytometry, MM Tumor cell killing |
| dilution | Flow Cyt 1:100; MMTumor cell killing |
| shipping | Shipped at ambient conditions. |
| storage | Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months. |
The basic principle of BiTE cell killing assay. The BiTE molecule can effectively bring T cells to tumor target cells and stimulate tumor cell killing activity of T cells.
A: The scheme of Anti-BCMA BiTE molecule. B: Tumor cell killing assay. NCI-H929 cells (stably transfected with luciferase), were incubated with freshly isolated human PBMC, and different concentration of BiTE antibodies constructed from rabbit Anti-Human BCMA/TNFRSF17 Clone DM4 (red line), or BB2121 originated huC11D5.3 clone (blue line) or a no BCMA binding clone as negative control (black line). After 48hrs incubation, the viable NCI-H929 tumor cells were measured by luciferase activity assay.
DMR1384-100ug
100ug
$657
DMR1384-500ug
500ug
$1,971