Mouse anti-Human Tau Monoclonal Antibody (Clone KT233)

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PRODUCT

  • SKU

    WZA1341-100ul

  • Size

    100uL

  • Price

    $795

1
This antibody was raised against a protein with Unprot Accession # P10636-8. It's core sequence is: MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
target Tau
host Mouse
reactivity Human, Rat, Mouse
clonality Monoclonal
clone number KT233
iso type IgG2b
conjugate Unconjugated
applications IHC, ICC, WB, ELISA
formulation Supplied as solution in phosphate buffered saline containing 0.09% sodium azide
dilution IHC 1:200, WB 1:1000, ELISA 1:250-1:500
shipping Ship at ambient conditions or with ice packs.
storage Store at 4°C. The antibody is stable for at least one month from date of shipment. For long-term storage, aliquote the antibody and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

Images

Cross reactivity test: Microtiter wells were coated with various peptides and recombinant proteins. KT233 was used as the primary antibody and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. Result: KT233 can detect Tau proteins regardless of phosphorylation.

ELISA: Microtiter wells were coated with K40031_11H5 at 3 ug/mL as the capture antibody. Recommbinant pTau181 Protein (Cat. P00003CA) was used as the antigen. Peroxidase conjugated pTau181 Antibody (KT233) was used as the detection antibody. Result: KT233 and K40031_11H5 can be used as a matched antibody pair to detect and quantify the concentration of MAPT .

Immunohistochemistry: IHC-P analysis of brain tissue by Tau antibody (KT233). IHC-P was performed using sections of the formalin-fixed paraffin-embedded brain tissue.

Western Blot: Various protein samples were run on 6-18% SDS-PAGE under reducing conditions and blotted onto nitrocellulose membrane. KT233 at 1 ug/mL was used as the primary antibody and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. Tau band was visualized using ECL Western Blotting Substrate. Lane 1: 15 ug of brain tissue lysate Lane 2: 15 ug of rat brain tissue lysate Lane 3: 15 ug of mouse brain tissue2 lysate Result: KT233 can detect Tau by Western blotting.


PRODUCT

  • SKU

    WZA1341-100ul

  • Size

    100uL

  • Price

    $795

1